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Inositol - Wikipedia

Inositol usually refers to Myo-inositol, a small molecule structurally similar to glucose that is involved in cellular signalling. It appears to be an. However, we recently showed that myo-inositol trispyrophosphate .. Design, synthesis, testing, and structure-allosteric activity relationship of. Buy myo-Inositol Trispyrophosphate Hexasodium Salt (CAS ), a membrane-permeant allosteric effector of hemoglobin, from Santa Cruz.

Metabolism Beyond Myo-inositol and epi-inositol there is D-chiro-inositol DCIconverted from myo-inositol via an epimerase [36] which is decreased in states of insulin resistance.

Neural Myo-inositol is normally present around mM concentrations in neural tissue in rats [39] and in humans it has been confirmed that myo-inositol is around 3. Depression and Mood In depressive and bipolar persons who have committed suicide, inositol concentrations in the frontal cortices seem to be reduced [45] and at least in depressive persons this has been noted in vivo. It appears moderately to weakly potent, and only seems transiently effective benefits stop upon supplement discontinuation In a study on bulimia and binge eating considered a mood disorder of sortssix weeks supplementation of high dose inositol 18g daily was able to significantly improve symptoms as assessed by the GCI and EDI rating scales, and both depressive and anxiety scores were also reduced more with inositol than with placebo.

There may be an interaction with TCA-based antidepressants 3.

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Premenstrual Syndrome Premenstrual dysphoric disorder is a mood disorder associated with PMS, [53] and supplementation of 4,mg myo-inositol thrice daily total dose of 12g or the bioequivalent dose in gel caps 1. It may require continued supplementation over a prolonged period of time 3.

Bipolar Disorder A trial using inositol at 12g daily as an add-on therapy for a period of six weeks failed to outperform placebo in reducing depressive and bipolar symptoms [55] although due to the observed trend towards significance it has been noted by some reviewers [56] [57] that larger trials are needed. Subsequently, a trial conducted using inositol in persons with bipolar disorder undergoing a major depressive episode noted that supplementation was associated with a Anxiety and Panic Disorders Inositol was initially found to be anxiolytic anxiety reducing in a rat model of the elevated maze plus test using myo-inositol [59] and later replicated by epi-inositol.

Schizophrenia The alterations seen in cerebrospinal fluid myo-inositol seen in depressive persons does not appear to extend to schizophrenic persons, as those with schizophrenia have the same concentration as healthy controls. Obsessive Compulsive Disorder OCD Supplementation of 18g inositol daily in persons with diagnosed obsessive compulsive disorder OCD over a period of six weeks has led to significant improvements in symptoms as assessed by the Yale-Brown Obsessive Compulsive Scale.

Locomotion While acute intravenous administration of inositol has mixed evidence for whether it works or not a failure [69] and increase [70]ingestion of around 1. Memory and Learning 6g of myo-inositol taken daily for five days prior to electroconvulsive therapy ECT failed to prevent ECT-induced losses in memory, suggesting no relevant anti-amnesiac effects. Alzheimer's Disease Scyllo-inositol is one of the steroisomers of inositol found in the brain [72] [73] and seems to accumulate in the brain with ageing, [74] being measured at 0.

Lipoproteins Plasmalogens are components of lipoproteins synthesized in the liver and known to be decreased in aging and hyperlipidemia [83] [84] as well as familial hypercholesterolemia. Energy Enhancement - Inositol can promote fat metabolism, protect myocardium and enhance energy 3.

Myo-inositol trispyrophosphate ITPP /CAS NO.:802590-64-3/Manufacturer supply

Healthy Hair - Inositol is necessary for hair growth, can promote healthu hair growth and prevent hair loss and baldness. Growth Promotion - The growth and survival of cells in the brain, bone marrow, eyes and intestines depends upon inositol. Inositol plays an important role to the healthy growth of the cell membrane.

Cholesterol Reduction - Inositol effective promotes the body's production of lecithin which can eliminate liver fat, therefore inositol is helpful in fat metabolism, reducing blood cholesterol and precenting atherosclerosis. Eczema Prevention - Reduce the severity of skin-related disorders such as eczema and psoriasis 7.

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A natural sedative - Inositol is a neurotransmitter, acting to the nervous system to help the relase of serotonin and acetycholine so to bring calming effect as a natural sedative. Mainly used to confect multi-vitamin pills and various nutritional amino acid-vitamin infusion products. In addition, it can also be used in the treatment of cirrhosis,hepatitis,fatty liver,arteriosclerosis,high cholesterol in the blood,high diabetes, carbon tetrachloride poisoning etc. Its anticancer effects are particularly remarkable.

It may be taken directly or used as nutrientdrinks or nutrient agent of food for children. It may stimulate themetabolism of human body,such as Red Bull. As a food additives, inositol is used for culture of various strains and promotion yeast growth.

Inositol is used for culture of various strains and promotion yeast growth,prevention of skin-aging and hair loss.